Computer Aided Diagnosis and Visualization have been widely used in several medical fields. In cardiology, there are currently two techniques used in the measurement of myocardial deformation in two dimensions: Tissue Doppler and 2D Strain. The first technique has drawbacks regarding the dependence on the angle of insonation of the transducer during the echocardiographic examination. The second technique, Speckle Tracking, consists of tracking the natural acoustic markers in the image produced by ultrasound. In this paper we perform a comparative analysis of time-delay estimators applied in synthetic and medical videos from echocardiographic examinations. The evaluation of the techniques is performed on the deformation (strain curves and strain rate) of phantoms and echocardiographic images and the results prove to be feasible to track speckle marks during the cardiac cycle
